Wednesday 15 February 2023

Secondary crises now greatest threat to life after earthquakes, says researcher

The death toll from the Turkey and Syria earthquakes has continued to climb, with more than 37,000 lives lost. This staggering number is likely to grow even higher over coming days as the rubble is cleared. The disaster is now among the top five most deadly earthquakes globally in the past two decades.

https://www.lifetechnology.com/blogs/life-technology-medical-news/secondary-crises-now-greatest-threat-to-life-after-earthquakes-says-researcher

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How records of life's milestones help solve cold cases, pinpoint health risks and allocate public resources

After 65 years, Philadelphia police announced in December 2022 that they had identified the remains of Joseph Augustus Zarelli, a 4-year-old boy who was murdered in 1957. Because no one had ever come forward to reliably identify Joseph, he became "America's Unknown Child," a moniker that captured the tragic anonymity of his early death.

https://www.lifetechnology.com/blogs/life-technology-medical-news/how-records-of-lifes-milestones-help-solve-cold-cases-pinpoint-health-risks-and-allocate-public-resources

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How to create better homes for autistic people with significant additional needs

Our homes are becoming smaller, darker and noisier. Access to outside space is at a premium, and housing trends are leading to lower square meterage, smaller windows and noisy open-plan home environments.

https://www.lifetechnology.com/blogs/life-technology-medical-news/how-to-create-better-homes-for-autistic-people-with-significant-additional-needs

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A way of life that keeps cells young in one region of Costa Rica

In Nicoya, Costa Rica, where average incomes are among the nation's lowest, the average life span is 85—among the world's highest. By comparison, a person in the United States can reasonably expect to live to just 77, according to federal census data.

https://www.lifetechnology.com/blogs/life-technology-medical-news/a-way-of-life-that-keeps-cells-young-in-one-region-of-costa-rica

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Tackling skin inflammation with vitamin D

High-dose oral vitamin D reduced skin inflammation and increased immunoprotection in patients with chemical-induced skin rashes, according to findings from a recent Northwestern Medicine clinical trial published in JCI Insight.

https://www.lifetechnology.com/blogs/life-technology-medical-news/tackling-skin-inflammation-with-vitamin-d

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Neoadjuvant nivolumab shows long-term benefit in patients with non–small cell lung cancer

Patients with resectable non–small cell lung cancer (NSCLC) who were treated with neoadjuvant nivolumab had improved five-year recurrence-free and overall survival rates compared with historical outcomes, according to results published in Clinical Cancer Research.

https://www.lifetechnology.com/blogs/life-technology-medical-news/neoadjuvant-nivolumab-shows-long-term-benefit-in-patients-with-non-small-cell-lung-cancer

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Why severe fatty liver leads to liver damage

In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes apoptosis whereas severe steatosis predominantly causes necroptosis leading to cell rupture. This induces strong inflammation and new cell death, producing further liver damage. We reveal the transcription factor ATF3 to be involved in this process. Our results are expected to contribute to therapeutic method development.

https://www.lifetechnology.com/blogs/life-technology-medical-news/why-severe-fatty-liver-leads-to-liver-damage

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Sensory cells taste cerebrospinal fluid to fight brain infections

Sensory neurons pick up information from our senses and relay it to the rest of the nervous system. But this is not their only mission. In a new study published in the journal Current Biology, Claire Wyart at the Paris Brain Institute, and Christina Vandenbroucke-Grauls at the Amsterdam University Medical Centers, have shown that sensory neurons in the central nervous system play a leading role in pneumococcal meningitis, a severe infection with a high mortality rate and strong epidemic potential. They help fight infection and promote host survival.

https://www.lifetechnology.com/blogs/life-technology-medical-news/sensory-cells-taste-cerebrospinal-fluid-to-fight-brain-infections

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Development of a low-power, long-term sweat sensor patch that imitates sensory neurons

Human sweat contains chemical information including blood metabolites, ion concentrations, and nutrients. Monitoring this information using a wearable sensor can allow non-invasive (i.e., without blood sampling), real time health status tracking. For example, knowing sweat volume and ion concentrations can help people maintain adequate water and sodium levels during physical activities, and can prevent hypoglycemic shock by identifying symptomatic excessive sweating.

https://www.lifetechnology.com/blogs/life-technology-medical-news/development-of-a-low-power-long-term-sweat-sensor-patch-that-imitates-sensory-neurons

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Survivors of Utah's eugenic sterilization program still alive in 2023

At least 830 men, women and children were coercively sterilized in Utah, approximately 54 of whom may still be alive. They were victims of a sterilization program that lasted for fifty years in the state and targeted people confined to state institutions. Many were teenagers or younger when operated upon; at least one child was under the age of ten.

https://www.lifetechnology.com/blogs/life-technology-medical-news/survivors-of-utahs-eugenic-sterilization-program-still-alive-in-2023

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