Saturday, 15 June 2019

PCSK9 inhibitors: Studies needed to prove efficacy and safety in chronic kidney disease

Chronic kidney disease (CKD) is associated with a substantially increased risk for the development of atherosclerotic cardiovascular disease (CVD). Accordingly, cardiovascular mortality is increased even in the earliest stages of CKD. In the general population and in CKD patients, high plasma levels of low-density lipoprotein cholesterol (LDL-C) are crucially involved in the initiation and progression of atherosclerotic vascular lesions. In addition, it has been documented that LDL accumulating in the vascular wall is prone to be post-translationally modified, for example, by oxidation or carbamylation, which is particularly relevant to patients with CKD.

* This article was originally published here

Elder abuse increasing, without increased awareness

About 16% of older adults are victims of some form of mistreatment and the number of reported cases of elder abuse is steadily increasing. Because of poor record-keeping, however, those of us who study elder abuse don't know if the trend reflects an actual increase, an increase because of growing numbers of older adults, or only an increase in reporting due to greater awareness.

* This article was originally published here

Womankind's giant leap: who will be the first female moonwalker?

Who will take the giant leap for womankind?

* This article was originally published here

PoseRBPF: A new particle filter for 6D object pose tracking

Researchers at NVIDIA, University of Washington, Stanford University, and University of Illinois Urbana-Champaign have recently developed a Rao-Blackwellized particle filter for 6-D pose tracking, called PoseRBPF. The approach can effectively estimate the 3-D translation of an object and its full distribution over the 3-D rotation. The paper describing this filter, pre-published on arXiv, will be presented at the upcoming Robotics Science and Systems Conference in Freiburg, Germany.

* This article was originally published here