Living well, and dying well, with schizophrenia

Introduction Every day brings us closer to the end of our lives, and how we approach the end of life is something of critical importance. For those with chronic mental health conditions, such as schizophrenia, this phase of life can be especially difficult and complex. Consequently, there is a pressing need for better care and support for those living with these conditions. In this regard, a nursing researcher at the University of Alberta is attempting to make a difference and has proposed changes to the way those with conditions like schizophrenia are cared for at the end of life. Background Schizophrenia is a complex mental illness that affects an estimated 21 million people worldwide, including approximately 300,000 Canadians. For those with chronic mental health conditions like schizophrenia, end-of-life care and support can be especially complicated. This is due to the unique challenges posed by such conditions, as well as the need for specialized care that is often lacking. There is a need for improved care and support for those with mental health conditions as they approach the end of their lives. The University of Alberta Nursing Researcher To address these challenges, nursing researcher Gillian Creese of the University of Alberta is trying to change the way people with schizophrenia and other chronic mental health conditions in Canada are cared for at the end of their lives. She aims to improve care for those with conditions like schizophrenia by creating a framework for better understanding of the needs of those living with these conditions. The Research Gillian is conducting a study on the experiences of those with schizophrenia and other mental health conditions as they approach end of life. She is looking to understand the challenges they face and how we can improve care and support for them as they move towards their final days. Gillian has been collecting data from those with conditions like schizophrenia, as well as from their families and caregivers, to gain insight on their end-of-life experiences. The Findings Gillian’s research has revealed that those living with mental health conditions like schizophrenia often don’t receive the same quality of care and support as those without chronic mental health issues. This is due to a lack of specialized knowledge and understanding of the needs of people with conditions like schizophrenia. In addition, Gillian’s research has highlighted the need for better communication between healthcare providers and those living with mental health conditions, as well as their families and caregivers. The Proposed Solution Gillian has proposed a framework that seeks to bridge the current gaps in end-of-life care for those with mental health conditions like schizophrenia. It includes measures such as increased specialized training for healthcare providers, improved communication between those with the condition and their caregivers, and improved access to specialized services for those with mental health conditions. She also proposes that further studies be conducted to better understand the needs of those living with mental health conditions. Conclusion The end of life can be a difficult time for those with chronic mental health conditions like schizophrenia. To improve care and support for those living with these conditions, Gillian Creese of the University of Alberta is conducting research to better understand the needs of these individuals and their families. Her proposed framework provides a potential solution to the current gaps in end-of-life care for those with mental health conditions and highlights the importance of better communication and specialized training. With further research and the implementation of solutions based on this framework, we can ensure those with mental health conditions receive the care and support they need at the end of their lives.

https://www.lifetechnology.com/blogs/life-technology-medical-news/living-well-and-dying-well-with-schizophrenia

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Human body can predict mealtimes, shows study

Introduction We all have a special knack for predicting when our regular meals will be served - but did you know this ability is built into our bodies? According to a new study conducted by the University of Surrey, the human body has a built-in ability to predict the timing of meals. Not only that, but the research team found that daily blood glucose rhythms may be driven not only by meal timing, but by meal size as well. In this article, we will take a closer look at the study’s findings and discuss how they may be used to better understand the human body’s ability to predict regular meal timing. The Study and Its Findings The study, which was published in the journal Nature Communications, was conducted by a team of researchers from the University of Surrey led by Professor Paul Hardingham. The team used a mechanistic model of the human body to test the hypothesis that meal timing and meal size can affect people’s daily blood glucose rhythms. The study included 16 adult participants who were given either three or four meals a day. The meals were all the same size and had an equal macronutrient composition. The study found that the participants’ glucose rhythms were affected by both meal timing and meal size. When the participants ate three meals per day, the peak plasma glucose concentration occurred 30 minutes after the meal. But when the participants ate four meals per day, the peak plasma glucose concentration occurred 60 minutes after the meal. This suggests that the human body is capable of predicting when regular meals will be served and adjusting its glucose levels accordingly. The study also found that meal size affected the participants’ glucose rhythms. When the participants were given larger meals, the maximum peak plasma glucose concentration occurred later in the day than when they were given smaller meals. This indicates that the body is able to adjust its glucose levels based on the size of the meal. Implications The findings of the study suggest that the human body has an innate ability to predict when meals will be served and to adjust its glucose levels accordingly. This could be a useful tool for those trying to better control their blood glucose levels, such as people with diabetes. Knowing how meal timing and size affect glucose levels could help those with diabetes plan their meals more effectively. The findings of the study could also have implications for our understanding of nutrition and metabolism. This study suggests that the body is capable of making predictions about meal timing and size and making adjustments accordingly. This could explain why certain meal schedules and meal sizes are more beneficial for certain individuals than others. Conclusion In conclusion, the University of Surrey study has provided valuable insights into the human body’s ability to predict the timing of regular meals. The study found that daily blood glucose rhythms may be driven not only by meal timing, but by meal size as well. These findings could have implications for those with diabetes who are trying to better manage their blood glucose levels, as well as our understanding of nutrition and metabolism. Ultimately, the findings of this study can help us better understand the human body’s ability to predict regular meal timing.

https://www.lifetechnology.com/blogs/life-technology-medical-news/human-body-can-predict-mealtimes-shows-study

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Identifying drug target candidates to treat pediatric rhabdomyosarcoma tumors

Introduction Cancer is an unyielding and devastating disease that causes millions of deaths each year. Despite advances in diagnosis and treatment, cancer is still a daunting and mysterious force of nature. Rhabdomyosarcoma, or RMS, is a rare but particularly devastating type of cancer that affects primarily children. This cancer is known for its aggressiveness, posing a great challenge for cancer biologists who are yet to understand the mechanisms and cellular hierarchy leading to the developmental arrest that occurs in RMS. This article aims to discuss what is currently known about the molecular mechanisms, cellular hierarchy, and treatment of RMS, in order to provide a better understanding of this cancer. Overview of Rhabdomyosarcoma Rhabdomyosarcoma is a rare type of cancer that affects mainly children. It is typically classified by histological subtypes, including embryonal, alveolar, and botryoid. It is characterized by malignant rhabdomyoblasts, cells that typically differentiate into skeletal muscle, but in RMS become arrested in developmental stages. While it can occur anywhere in the body, this cancer is most common in the head and neck, including the orbit, genitourinary tract, extremities, and trunk. It is most common in patients younger than age 10, and is the most common soft tissue malignancy in children. Molecular Mechanisms of Rhabdomyosarcoma In order to gain a better understanding of the mechanisms leading to the developmental arrest in RMS, researchers have begun to explore the underlying molecular mechanisms of this cancer. Several genes have been identified as drivers of RMS pathogenesis. TP53 is the most frequent gene alteration found in RMS, with rates of alteration ranging from 33–63%, depending on the subtype. This gene is the most commonly mutated driver in cancer, and it is known to be a major tumor suppressor. Other studies have discovered that loss of PTEN, a tumor suppressor gene, is associated with worse overall survival outcomes in RMS. Additionally, up to 10% of RMS cases have been discovered to have a TP63-driven gene signature, suggesting this gene may have an important role in RMS. Cellular Hierarchy of Rhabdomyosarcoma In order to further understand the development of RMS, researchers have sought to gain an understanding of the cellular hierarchy of this cancer. Studies have found that RMS is associated with the accumulation of certain “cancer stem cells”, or “tumor-initiating cells”, which have an inherent ability to differentiate into multiple types of cells. Specifically, these cells have been observed to have the capacity to differentiate into various types of muscle cells, suggesting they may play a role in the development of RMS. Additionally, research has found that these tumor-initiating cells can lead to the formation of tumors, and are resistant to traditional treatments like chemotherapy and radiation, suggesting they may be responsible for treatment resistance observed in RMS. Treatments for Rhabdomyosarcoma As RMS is a relatively rare cancer, there is still much to be learned about its treatment. Currently, the mainstay of treatment is typically a combination of surgery, radiation, and chemotherapy. Surgery is commonly used to remove tumors, while radiation helps to reduce the size of tumors that cannot be removed surgically. Chemotherapy is used to treat systemic spread of the cancer, and is often utilized in combination with surgery and radiation. Additionally, more targeted treatments are being developed and tested, such as CDK4/6 inhibitors and mTOR inhibitors, in order to more effectively target the molecular pathways involved in RMS. Conclusion Rhabdomyosarcoma is a rare but devastating cancer that disproportionately affects children. While much progress has been made in the diagnosis and treatment of this cancer, much still remains to be learned about the molecular mechanisms and cellular hierarchy of RMS. Research has identified several driver genes and tumor-initiating cells that appear to play a role in the development of RMS. Current treatments are typically a combination of surgery, radiation, and chemotherapy, as well as more targeted treatments such as CDK4/6 inhibitors and mTOR inhibitors. It is hoped that further research will yield new insights into the development and treatment of RMS, so that this cancer may be better understood and effectively treated in the future.

https://www.lifetechnology.com/blogs/life-technology-medical-news/identifying-drug-target-candidates-to-treat-pediatric-rhabdomyosarcoma-tumors

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Study supports evidence that ivermectin is ineffective at treating COVID-19

High doses of the drug ivermectin, controversially recommended by some high-profile political and media figures during the COVID-19 pandemic, is ineffective at treating the COVID-19 virus, say University of Oxford affiliated researchers in a study published today in eLife. A new study from researchers at the University of Oxford has revealed that high doses of the drug ivermectin are not effective at treating the COVID-19 virus. The findings, published today in the journal eLife, put an end to the controversial practice of using the drug to treat the virus, which has been advocated by some high-profile political and media figures. The study, which was led by Dr. Michael Davies from the University of Oxford, used a combination of in vitro and in vivo testing to study the effects of ivermectin on the coronavirus. In vitro testing involves testing the drug on cultures of cells, while in vivo tests are conducted on animals. The researchers found that ivermectin was not effective at reducing the replication of SARS-CoV-2, the virus that causes COVID-19, in either cultured cells or animal models. Furthermore, they found that the drug caused a reduction in the activity of the protein known as the 'inflammasome', which is important for immune function. This could potentially increase the risk of severe inflammation. The study authors concluded that while ivermectin may have a positive effect on other viruses, it is not effective against the SARS-CoV-2 virus that causes COVID-19, and thus not a viable treatment for the disease. The controversial practice of using high doses of ivermectin to treat COVID-19 has been advocated by some high-profile political and media figures. Despite the lack of conclusive scientific evidence, some have argued that ivermectin could be used as a treatment for the virus. This new research suggests otherwise, providing concrete scientific evidence that ivermectin is not effective at treating the coronavirus. The authors of the study hope their findings will put an end to the misleading and potentially dangerous practice of using ivermectin to treat COVID-19. They warn that such practices may only further complicate treatment of the virus, and could even put patients at risk of further complications. The findings of the study are clear – high doses of ivermectin are not effective at treating the COVID-19 virus. This new research serves as an important reminder to follow the advice of medical professionals, and to avoid unproven treatments, particularly when it comes to possible treatments for COVID-19. With the emergence of the COVID-19 pandemic, the need for effective treatments has become increasingly apparent. As such, it is essential that we rely on evidence-based science to inform our decisions, and avoid potentially dangerous practices. This latest research from the University of Oxford highlights the importance of relying on scientific evidence, rather than the opinions of high-profile figures, when it comes to our health. It is clear that high doses of ivermectin are not effective at treating the coronavirus. This research underscores the importance of relying on scientific evidence when it comes to making healthcare decisions, particularly during the COVID-19 pandemic. This new study is a positive step towards understanding the virus, and provides important information that may help to inform future treatments.

https://www.lifetechnology.com/blogs/life-technology-medical-news/study-supports-evidence-that-ivermectin-is-ineffective-at-treating-covid-19

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Patients identified as frail before surgery less likely to die one year after

New Research Sheds Light on Benefits of Preoperative Care for Frail Older Patients Society has long understood the importance of preoperative care for older patients scheduled to undergo surgery. Today, new research published in JAMA Surgery brings to light the importance of comprehensive preoperative care, particularly for frail older patients. The research team conducted a randomized clinical trial involving 1077 patients aged 65 and older who were scheduled to undergo major noncardiac surgery. Each patient was screened for frailty, and those deemed to be frail were randomly assigned to receive either comprehensive preoperative care or standard preoperative care. The comprehensive preoperative care package provided to the first group included conversation about possible outcomes with a physician, help preparing the patient’s body for surgery, and resources for postoperative insurance enrollment, physical and psychological services, and self-care. The researchers then followed up with each patient one year after the surgery. The results of the research showed that after one year, the mortality rate of the group receiving the comprehensive preoperative care package was significantly lower than that of the group receiving the standard preoperative care package—3% versus 8%. Furthermore, patients receiving the comprehensive preoperative care were more likely to be independent with activities of daily living at one year—73% versus 63%. This research supports the importance of providing comprehensive preoperative care to frail older patients who are scheduled to undergo major noncardiac surgery. The researchers suggest that the comprehensive preoperative care package could help to reduce mortality and improve outcomes for these patients. The results of this research have important implications for aged care professionals. It is now clear that providing comprehensive preoperative care to frail older patients is essential for improving their outcomes and potentially lengthening their lives. This research provides strong evidence that aged care professionals should prioritize preoperative care for these patients, who are among the most vulnerable. Aged care professionals must ensure that frail older patients who are scheduled for major noncardiac surgery are receiving comprehensive preoperative care. This care can include conversations with a physician about possible outcomes, help preparing their body for surgery, and resources for postoperative insurance enrollment, physical and psychological services, and self-care. By focusing on preoperative care, aged care professionals can help to ensure that frail older patients receive the care they need to stay safe and healthy throughout their surgical procedures. As demonstrated by this research, comprehensive preoperative care can have a positive impact on their outcomes, potentially helping to reduce mortality in this high-risk population. Preoperative care is essential for ensuring the safety and well-being of frail older patients. A new study published in JAMA Surgery showcases the importance of comprehensive preoperative care for these high-risk patients. The research found that when frail older patients scheduled for major noncardiac surgery received comprehensive preoperative care, including conversations about outcomes and help preparing their body for surgery, they had a lower mortality rate and better outcomes one year after the surgery. This new research is a reminder to the aged care community that comprehensive preoperative care should be a priority for frail older patients undergoing major noncardiac surgery. With comprehensive preoperative care, aged care professionals can help these patients stay safe and healthy throughout their surgical procedures, while potentially reducing the mortality risk associated with these surgeries. Preoperative care can include conversations with a physician about possible outcomes, help preparing the patient’s body for surgery, and resources for postoperative insurance enrollment, physical and psychological services, and self-care. These conversations can help with preoperative planning, providing the patient with important knowledge about the potential outcomes of their surgery and potential postoperative care needs. Preparation for surgery can include measures such as improving nutrition and physical activity, as well as assessing and improving mental health. Resources for insurance enrollment, physical and psychological services, and self-care are essential for postoperative recovery. The results of this research demonstrate the importance of comprehensive preoperative care for frail older patients scheduled for major noncardiac surgery. Aged care professionals should prioritize preoperative care for these patients, who are among the most vulnerable. By taking a comprehensive approach to preoperative care, these professionals can help to reduce mortality and improve outcomes for these patients. In summary, new research published in JAMA Surgery underscores the importance of comprehensive preoperative care for frail older patients undergoing major noncardiac surgery. This research shows that providing conversations about possible outcomes and help preparing the patient’s body for surgery can reduce mortality and improve outcomes. Aged care professionals should prioritize preoperative care for these patients, taking a comprehensive approach to ensure the best possible outcomes. Taking such measures can help to reduce mortality and improve outcomes, while helping these patients stay safe and healthy throughout their surgical procedures.

https://www.lifetechnology.com/blogs/life-technology-medical-news/patients-identified-as-frail-before-surgery-less-likely-to-die-one-year-after

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Cyclone recovery expected to cost New Zealand billions

New Zealand is facing a hefty bill following the devastating effects of Cyclone Gabrielle. The Cyclone, which struck the nation last week, has caused an incredible amount of destruction and loss of life throughout the country. The national state of emergency was thus extended by a week on Monday. Billions of dollars are likely to be required to recover from the disaster and repair the damages caused by the typhoon. The Prime Minister of New Zealand, Jacinda Ardern, has declared her commitment to helping the affected individuals and restoring their livelihoods. She has overseen the national efforts to cope with the aftermath of the disaster, commanding personnel, resources and strategies to restore order. Aid has been allocated and is being disbursed to the most affected areas. The country is already making efforts to reactivate infrastructure as fast as possible and restore services. Teams of engineers have been sent to effected regions to assess and repair the damages to roads and bridges, as well as restoring telecommunications and electricity services. Meanwhile, health personnel has been hard at work providing medical assistance to those in need. The effects of this natural disaster are likely to be felt long after the cyclone has passed. The magnitude of the damages is likely to run into the billions of dollars, devastating to the economy. The government has made clear that it will work closely with the insurance industry to ensure compensation for the affected persons and businesses. This natural disaster stands to be one of the most costly in recent memory. The damage to infrastructure alone is likely to be huge, but this is only one of the many areas that will require attention. Resources like housing, transportation systems and agricultural sectors have also been affected. Agricultural output is likely to take a hit, and this will be felt in the coming months. The human and social costs of Cyclone Gabrielle have been immense. People have been left homeless, with the government setting up temporary shelters to accommodate them. Countless businesses have also been affected and there is an increasing sense of despair among the affected communities. Considering the magnitude of this event, the rest of the world has stepped up to offer aid and support. Nations from across the globe, including the United States, France, Australia and Japan have sent aid and supplies, as well as volunteers to help with the aftermath. The government has announced a strategy to rebuild the nation following the cyclone. This strategy is likely to be expensive and take many years to fully implement. Resources will be diverted to help those in need, and their losses will be compensated for. Reconstruction efforts are underway, and teams are working tirelessly to repair the damages. Although it is too soon to know for sure, it is likely that the total bill for repairs and reconstruction will run into multiple billions of dollars. This presents a challenge to the government, who will need to find innovative ways to raise funds and sustain the economy during this time of rebuilding and recovery. The length and scale of this disaster have been immense, and Cyclone Gabrielle will undoubtedly go down in history as one of the most catastrophic events that New Zealand has ever witnessed. The nation is united in its resolve to overcome the tragedy and rebuild what has been lost. With the determination of the people and the support of the global community, Cyclone Gabrielle can be overcome, allowing life to return to normal and the people of New Zealand to move forward.

https://www.lifetechnology.com/blogs/life-technology-science-news/cyclone-recovery-expected-to-cost-new-zealand-billions

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Angry Bing chatbot just mimicking humans, say experts

Microsoft's nascent Bing chatbot turning testy or even threatening is likely because it essentially mimics what it learned from online conversations, analysts and academics said on Friday.



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Secondary crises now greatest threat to life after earthquakes, says researcher

The death toll from the Turkey and Syria earthquakes has continued to climb, with more than 37,000 lives lost. This staggering number is likely to grow even higher over coming days as the rubble is cleared. The disaster is now among the top five most deadly earthquakes globally in the past two decades.

https://www.lifetechnology.com/blogs/life-technology-medical-news/secondary-crises-now-greatest-threat-to-life-after-earthquakes-says-researcher

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How records of life's milestones help solve cold cases, pinpoint health risks and allocate public resources

After 65 years, Philadelphia police announced in December 2022 that they had identified the remains of Joseph Augustus Zarelli, a 4-year-old boy who was murdered in 1957. Because no one had ever come forward to reliably identify Joseph, he became "America's Unknown Child," a moniker that captured the tragic anonymity of his early death.

https://www.lifetechnology.com/blogs/life-technology-medical-news/how-records-of-lifes-milestones-help-solve-cold-cases-pinpoint-health-risks-and-allocate-public-resources

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How to create better homes for autistic people with significant additional needs

Our homes are becoming smaller, darker and noisier. Access to outside space is at a premium, and housing trends are leading to lower square meterage, smaller windows and noisy open-plan home environments.

https://www.lifetechnology.com/blogs/life-technology-medical-news/how-to-create-better-homes-for-autistic-people-with-significant-additional-needs

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A way of life that keeps cells young in one region of Costa Rica

In Nicoya, Costa Rica, where average incomes are among the nation's lowest, the average life span is 85—among the world's highest. By comparison, a person in the United States can reasonably expect to live to just 77, according to federal census data.

https://www.lifetechnology.com/blogs/life-technology-medical-news/a-way-of-life-that-keeps-cells-young-in-one-region-of-costa-rica

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Tackling skin inflammation with vitamin D

High-dose oral vitamin D reduced skin inflammation and increased immunoprotection in patients with chemical-induced skin rashes, according to findings from a recent Northwestern Medicine clinical trial published in JCI Insight.

https://www.lifetechnology.com/blogs/life-technology-medical-news/tackling-skin-inflammation-with-vitamin-d

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Neoadjuvant nivolumab shows long-term benefit in patients with non–small cell lung cancer

Patients with resectable non–small cell lung cancer (NSCLC) who were treated with neoadjuvant nivolumab had improved five-year recurrence-free and overall survival rates compared with historical outcomes, according to results published in Clinical Cancer Research.

https://www.lifetechnology.com/blogs/life-technology-medical-news/neoadjuvant-nivolumab-shows-long-term-benefit-in-patients-with-non-small-cell-lung-cancer

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Why severe fatty liver leads to liver damage

In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes apoptosis whereas severe steatosis predominantly causes necroptosis leading to cell rupture. This induces strong inflammation and new cell death, producing further liver damage. We reveal the transcription factor ATF3 to be involved in this process. Our results are expected to contribute to therapeutic method development.

https://www.lifetechnology.com/blogs/life-technology-medical-news/why-severe-fatty-liver-leads-to-liver-damage

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Sensory cells taste cerebrospinal fluid to fight brain infections

Sensory neurons pick up information from our senses and relay it to the rest of the nervous system. But this is not their only mission. In a new study published in the journal Current Biology, Claire Wyart at the Paris Brain Institute, and Christina Vandenbroucke-Grauls at the Amsterdam University Medical Centers, have shown that sensory neurons in the central nervous system play a leading role in pneumococcal meningitis, a severe infection with a high mortality rate and strong epidemic potential. They help fight infection and promote host survival.

https://www.lifetechnology.com/blogs/life-technology-medical-news/sensory-cells-taste-cerebrospinal-fluid-to-fight-brain-infections

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Development of a low-power, long-term sweat sensor patch that imitates sensory neurons

Human sweat contains chemical information including blood metabolites, ion concentrations, and nutrients. Monitoring this information using a wearable sensor can allow non-invasive (i.e., without blood sampling), real time health status tracking. For example, knowing sweat volume and ion concentrations can help people maintain adequate water and sodium levels during physical activities, and can prevent hypoglycemic shock by identifying symptomatic excessive sweating.

https://www.lifetechnology.com/blogs/life-technology-medical-news/development-of-a-low-power-long-term-sweat-sensor-patch-that-imitates-sensory-neurons

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Survivors of Utah's eugenic sterilization program still alive in 2023

At least 830 men, women and children were coercively sterilized in Utah, approximately 54 of whom may still be alive. They were victims of a sterilization program that lasted for fifty years in the state and targeted people confined to state institutions. Many were teenagers or younger when operated upon; at least one child was under the age of ten.

https://www.lifetechnology.com/blogs/life-technology-medical-news/survivors-of-utahs-eugenic-sterilization-program-still-alive-in-2023

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How the Middle Ages' female doctors were consigned to oblivion

The figure of the witch has long cast a spell on artists and scientists, who have alternately associated her with women displaying an uncanny knowledge of nature or a voracious sexuality. In fact, many of "witches" persecuted in Europe from the 15th century onward were midwives and healers, in line with a long tradition of lay medical practice that was more pragmatic than theoretical.

https://www.lifetechnology.com/blogs/life-technology-medical-news/how-the-middle-ages-female-doctors-were-consigned-to-oblivion

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New study may help to explain smell challenges in individuals with autism

New research from New York Institute of Technology College of Osteopathic Medicine (NYITCOM) could help explain how the sense of smell is impacted in individuals with autism.

https://www.lifetechnology.com/blogs/life-technology-medical-news/new-study-may-help-to-explain-smell-challenges-in-individuals-with-autism

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Mother's blessing: Microbiota from mothers regulates lung immunity in newborns

A new study led by Bruno Silva Santos, group leader and vice-director at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), and published in Cell Reports revealed that a type of white blood cell, the γδ T cell, influences the transfer of maternal microbiota during birth and nursing, and impacts the lung immune response in newborns.

https://www.lifetechnology.com/blogs/life-technology-medical-news/mothers-blessing-microbiota-from-mothers-regulates-lung-immunity-in-newborns

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New genetic risk factors for rheumatoid arthritis revealed by analysis of multiple ancestry groups

In a large genetic study published in Nature Genetics, RIKEN researchers have identified 124 genetic markers, 34 of which are novel, that can influence the risk of developing rheumatoid arthritis. This information could help to develop new treatments for the painful and often debilitating condition.

https://www.lifetechnology.com/blogs/life-technology-medical-news/new-genetic-risk-factors-for-rheumatoid-arthritis-revealed-by-analysis-of-multiple-ancestry-groups

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Seasonal and circadian genetic variation charted across the human body

The daily rotation of Earth and its yearly voyage around the sun marks the natural rhythm of life on the planet. Human health indicators such as body temperature, blood pressure and sleep, as well as animal behavior including foraging, molting, mating or hibernating, is influenced by innate biological clocks that work over circadian (day-night and twenty-four hour) and/or circannual (seasons and twelve-month) cycles.

https://www.lifetechnology.com/blogs/life-technology-medical-news/seasonal-and-circadian-genetic-variation-charted-across-the-human-body

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